Synaptic plasticity lies at the heart of the brain's remarkable capacity to adapt and learn. It refers to the ability of synapses, the junctions between neurons, to undergo structural and functional changes in response to neuronal activity. Long-term potentiation (LTP) and long-term depression (LTD) are two primary forms of synaptic plasticity that play pivotal roles in learning and memory processes. LTP involves the strengthening of synaptic connections, leading to enhanced neuronal communication, while LTD results in the weakening of synaptic connections. These mechanisms underlie the brain's ability to encode and store information, forming the basis of learning and memory. Beyond its role in normal brain function, synaptic plasticity is implicated in various neurological and psychiatric disorders. Dysregulation of synaptic plasticity has been implicated in conditions such as Alzheimer's disease, schizophrenia, depression, and addiction, highlighting the importance of understanding these mechanisms in disease pathogenesis and treatment development. Researchers are exploring novel strategies to modulate synaptic plasticity for therapeutic purposes, aiming to restore normal synaptic function in diseased states. These efforts hold promise for the development of targeted interventions that address the underlying neural deficits associated with neurological and psychiatric disorders, ultimately improving patients lives.
Title : Personalized and Precision Medicine (PPM), as a unique healthcare model through biodesign-driven biotech and biopharma, translational applications, and neurology-related biomarketing to secure human healthcare and biosafety
Sergey Victorovich Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : Narrative medicine: A communication therapy for the communication disorder of Functional Seizures (FS) [also known as Psychogenic Non-Epileptic Seizures (PNES)]
Robert B Slocum, University of Kentucky HealthCare, United States
Title : Neuro sensorium
Luiz Moutinho, University of Suffolk, United Kingdom
Title : GBF1 inhibition reduces amyloid-beta levels in viable human postmortem Alzheimer's disease cortical explant and cortical organoid models
Sean J Miller, Yale School of Medicine, United States
Title : Study of resilience in cases of incest, father-daughter, step-father and step-daughter in the pre-pubber and puberous period among adult women and mothers: How to overcome the traumatisms of an incestuous relationship?
Daniele Lapointe, Laval University, Canada
Title : Traumatic Spinal Cord Injuries (tSCI) - Are the radiologically based “advances” in the management of the injured spine evidence-based?
W S El Masri, Keele University, United Kingdom