Synaptic plasticity lies at the heart of the brain's remarkable capacity to adapt and learn. It refers to the ability of synapses, the junctions between neurons, to undergo structural and functional changes in response to neuronal activity. Long-term potentiation (LTP) and long-term depression (LTD) are two primary forms of synaptic plasticity that play pivotal roles in learning and memory processes. LTP involves the strengthening of synaptic connections, leading to enhanced neuronal communication, while LTD results in the weakening of synaptic connections. These mechanisms underlie the brain's ability to encode and store information, forming the basis of learning and memory. Beyond its role in normal brain function, synaptic plasticity is implicated in various neurological and psychiatric disorders. Dysregulation of synaptic plasticity has been implicated in conditions such as Alzheimer's disease, schizophrenia, depression, and addiction, highlighting the importance of understanding these mechanisms in disease pathogenesis and treatment development. Researchers are exploring novel strategies to modulate synaptic plasticity for therapeutic purposes, aiming to restore normal synaptic function in diseased states. These efforts hold promise for the development of targeted interventions that address the underlying neural deficits associated with neurological and psychiatric disorders, ultimately improving patients lives.
Title : Scalp acupuncture with functional electrical stimulation for the treatment children with autism spectrum disorder
Zhenhuan Liu, Guangzhou University of Chinese Medicine, China
Title : Music therapy combined with acupuncture therapy for children with autism spectrum disorder
Zhenhuan Liu, Guangzhou University of Chinese Medicine, China
Title : Diquat exposure induces brainstem demyelination and encephalopathy via upregulating the mitochondrial calcium uniporter
Weixia Duan, The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, China
Title : Transcranial direct current stimulation (TDCS) for chronic migraine: a randomized clinical trial with 20 patients.
Milton C R Medeiros, Hospital Santa Casa de Arapongas, Brazil
Title : A computational approach to evaluate the impact of chemical pathways on brain activity on a broad scale.
Rahul Hajare, Sandip University, India
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Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation