Epilepsy and seizure disorders encompass a range of neurological conditions characterized by abnormal brain activity, leading to recurrent seizures. These disorders can vary in severity, from occasional, brief seizures to continuous, debilitating episodes. Advances in the understanding of epilepsy have focused on the genetic, environmental, and cellular mechanisms that contribute to the development of seizure activity, including ion channel dysfunction and neurotransmitter imbalances. Treatment strategies primarily involve antiepileptic drugs, but surgery, vagus nerve stimulation, and dietary therapies are also utilized for patients with refractory epilepsy. Ongoing research is investigating novel therapies, such as gene therapy and personalized medicine, to address the underlying causes of epilepsy and provide more effective treatments for seizure control and management.