Neurology and systemic disorders focuses on the intricate relationship between neurological conditions and other systemic diseases, highlighting how disorders affecting organs like the heart, kidneys, and liver can influence brain function. Systemic diseases such as diabetes, hypertension, and autoimmune disorders often have a direct impact on the nervous system, contributing to complications like stroke, neuropathy, and cognitive decline. Advances in research are uncovering the mechanisms by which these systemic conditions affect brain health, including the role of inflammation, vascular changes, and metabolic disruptions. By exploring these connections, the field is developing integrated treatment strategies that address both neurological and systemic health, improving overall patient outcomes. Personalized medicine, which considers the interdependence of different organ systems, is paving the way for more effective therapies for individuals with comorbid neurological and systemic disorders.