Cellular and systems neuroscience investigates the intricate workings of the brain at both the cellular and systems levels, focusing on how individual neurons and their networks contribute to brain function and behavior. At the cellular level, this field explores the role of neurotransmitters, ion channels, and synaptic plasticity in transmitting and processing information within the nervous system. At the systems level, researchers study how large-scale networks of neurons, such as those involved in sensory processing, motor control, and cognitive functions, communicate and integrate signals. Understanding these processes is essential for unraveling the mechanisms behind neurological disorders like epilepsy, schizophrenia, and Parkinson's disease. Advances in neuroimaging, optogenetics, and electrophysiology are providing new insights into how cellular and systems-level dysfunctions contribute to disease and guiding the development of novel therapeutic approaches.