Patients with Functional Seizures (FS) (also known as Psychogenic Non-Epileptic Seizures (PNES), have involuntary paroxysmal episodes that resemble epileptic seizures but without organic etiology. Many patients with FS have a history of sexual, physical, or emotional abuse, or ot [....] » Read More
The presentation starts with coverage of Advanced Neuroimaging and Neuro Technologies. Next, there will be an introduction to Behavioural Neuroscience, Gut-brain-axis, Microbiome, computational neuroscience and neurology. The discussion will the move on to dissecting concepts lik [....] » Read More
Prior to WWII the majority patients with tSCI died in hospitals. There was however no shortage of Clinicians experimenting with the management of the injured spine. During WWII L. Guttmann (a well-trained aggressive Neurosurgeon) was given the task of looking after injured soldie [....] » Read More
Background: Autism Spectrum Disorders (ASD) are a series of neurodevelopmental disorders characterized by social disorders, rigid behaviors and narrow interests. The World Health Organization (WHO) estimates that the prevalence of ASD has been increasing over the past 50 years. W [....] » Read More
Brain cancer and its treatments bring a unique threat to the patient’s identity and quality of life by challenging their essential identity in significant ways, possibly including impaired cognitive skills, loss of memory, reduced coordination, altered feeling states, and l [....] » Read More
Objective: To investigate the effect of and Acupuncture on brain plasticity and motor development in children with cerebral palsy. Investigate effect on mechanism of apoptosis of brain nerve cells, regulating the expression of neurotrophic factors, promoting the remodeling of ner [....] » Read More
As a plant flavonoid compound, chrysin comes from Scutellaria Baicalensis Georgi (Huangqin), which has a powerful immunoprotective effect to suppress immune inflammatory responses, and plays an outstanding role in the treatment of various brain diseases. This study aims to explor [....] » Read More
Diquat (DQ) is a widely used new herbicide that poses a great threat to the environment, ecological systems and human health. Although the Central Nervous System (CNS) is a sensitive target of DQ exposure, the major brain regions, pathological changes and underlying mechanisms of [....] » Read More
Growth Differentiation Factor 15 (GDF15) is a well-recognized neurotrophic and regulatory factor. Serum levels of GDF15 are an independent risk factor for stroke and an effective predictor of ischemic stroke outcomes. Currently, there is a lack of research on the mechanism of GDF [....] » Read More
This research delves into the primary question: How can psychodermatology be incorporated into regular dermatology clinics to make it more accessible for patients and why is it important to do so? This question is crucial because nearly one third of skin conditions are affiliated [....] » Read More
Neurodegenerative diseases such as Alzheimer's Disease and Parkinson's Disease (PD) are progressive conditions that affect the nervous system. All these diseases are characterized by the progressive loss of neurons in more or ess localized regions of the nervous system, l [....] » Read More
Background: LGI1 antibody-associated autoimmune encephalitis is a rare condition typically affecting older adults, presenting with seizures, cognitive decline, and behavioral changes. Diagnosis is often delayed due to normal imaging, EEG, and CSF findings. Early recognition and i [....] » Read More
Title : Perception and individuality in patient cases identifying the ongoing evolution of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Ken Ware, NeuroPhysics Therapy Institute, Australia
The way individuals perceive and interpret their internal and external environments directly influences how they function and adapt within them. In a stable and well-regulated human system, perception tends to align closely with reality, allowing for accurate motor responses and [....] » Read More
Title : Personalized and Precision Medicine (PPM), as a unique healthcare model through biodesign-driven biotech and biopharma, translational applications, and neurology-related biomarketing to secure human healthcare and biosafety
Sergey Victorovich Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Over the course of history, healthcare and thus healthcare philosophy have been focused predominantly on efforts to probe the already diseased individual by focusing down on a type of disorder (nosology) rather than on health or so-called pre-illness conditions. Much less effort [....] » Read More
Title : GBF1 inhibition reduces amyloid-beta levels in viable human postmortem Alzheimer's disease cortical explant and cortical organoid models
Sean J Miller, Yale School of Medicine, United States
Aging is a leading risk factor for the onset and progression of Alzheimer’s disease, characterized by key histopathological features such as amyloid-beta aggregation and Tau protein tangles. Amyloid-beta species are generated through the proteolytic cleavage of Amyloid Prec [....] » Read More
Title : Study of resilience in cases of incest, father-daughter, step-father and step-daughter in the pre-pubber and puberous period among adult women and mothers: How to overcome the traumatisms of an incestuous relationship?
Daniele Lapointe, Laval University, Canada
Sexual abuse of a child is a form of maltreatment. Among recent studies in this area, the Canadian study (Burczycka and Conroy, 2017) indicates that 70.3% are intrafamilial abuse and that of all cases of sexual abuse, 81% of victims are female (Silva and Collin-Vézina, 201 [....] » Read More
Title : Transcranial Direct Current Stimulation (tDCS) for chronic migraine: A randomized clinical trial with 20 patients
Milton Cesar Rodrigues Medeiros, Hospital Santa Casa de Arapongas, Brazil
Background: Chronic migraine is a disabling and often treatment-resistant neurological disorder. Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation technique with emerging evidence for pain management. To assess the efficacy and safety of anodal tDCS [....] » Read More
Title : Antibody-proteases as translational tools of the next-step generation to be applied through biodesign-driven translational biotech in personalized and precision neurology practice
Sergey Victorovich Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Multiple Sclerosis (MS) is a complex neurodegenerative pathology featuring with inflamma-tion, demyelination, and neurodegeneration. Due to the heterogeneity of MS-related clinical and even subclinical subtypes, their diagnosis becomes challenging and the best treatment cannot be [....] » Read More
Title : Neuroprotective potential of a traditional Uttarakhand plant against lambda-cyhalothrin-induced neural impairment: A pharmacological investigation
Mandeep Kumar Arora, DIT University, India
Neurodegenerative disorders are a group of diseases characterized by the progressive loss of structure or function of neurons, including brain cells, leading to impaired movement, cognition, and other neurological functions. Several factors contribute to the progression of neurod [....] » Read More
Title : A computational approach to evaluate the impact of chemical pathways on brain activity on a broad scale
Rahul Hajare, Sandip University, India
One of the most important problems in modern neuroscience is determining how pharmacological substances affect brain function. There is currently no methodical way to assess these effects in whole-brain models, which usually concentrate on macroscopic phenomena, whereas pharmaceu [....] » Read More
Title : AI-assisted collective analysis of neurological biomarkers: A study for enhanced diagnostic accuracy in neurodegenerative disorders
Raul Villamarin Rodriguez, Woxsen University, India
Neuromorphic Collective Intelligence System for Enhanced Neurological Diagnostic Accuracy. Background: Traditional neurological diagnosis relies heavily on individual clinician expertise, leading to significant variability in diagnostic accuracy across institutions and special [....] » Read More
Title : Standardization of the cognitive reaction test: Verification of its reliability and utility in the diagnosis of mild cognitive impairment
Carlos Alberto Mangone, Santojanni General Hospital, Argentina
Introduction: Early diagnosis of patients with Mild Cognitive Impairment (MCI) is essential to initiate early treatments that may slow their progression towards dementia. Because accurate biological and imaging markers are not accessible to all healthcare systems, neuropsychologi [....] » Read More
Title : Altered time-frequency feature of temporal lobe epilepsy based on improved hilbert-huang transform
Siyao Hao, Shandong Normal University, China
Background and Purpose: Temporal Lobe Epilepsy (TLE) is a neurological disorder with abnormal discharges in the temporal region of the brain. However, the abnormalities in the time-frequency features of brain regions in TLE has not yet been revealed. Hilbert-Huang Transform (HHT) [....] » Read More
Title : Decoding autism heterogeneity: Dynamic semi-supervised clustering identifies patterns and pathways
Siyao Hao, Shandong Normal University, China
Heterogeneity of Autism Spectrum Disorder (ASD) is a challenge for precision diagnosis or prognosis, thus motivating neurosubtyping and dimensional efforts. Nevertheless, most dimensional studies remain limited to identifying ASD-related patterns, especially using static brain co [....] » Read More
Title : Investigating the therapeutic potential of moringa oleifera bioactive compounds in NF-κB-mediated autism pathogenesis
Aanjaneya Mamgain, National Institute of Pharmaceutical Education And Research, India
Nuclear Factor-Kappa B (NF-κB) is a key regulator of inflammation and apoptosis implicated in the pathogenesis of Autism Spectrum Disorder (ASD). Aberrant NF-κB activation has been observed in the brain, particularly in microglia, and peripheral blood of individuals w [....] » Read More
Title : Modulation of neuroinflammatory pathways and oxidative stress by rhododendron arboreum extract in stress-induced postpartum depression
Anglina Kisku, DIT University, India
Postpartum Depression (PPD) is a complex neuropsychiatric disorder frequently precipitated by chronic stress, with its pathophysiology involving the kynurenine pathway, neuroinflammation, and oxidative stress. Conventional antidepressants often exhibit limited efficacy and are as [....] » Read More