Neurodegenerative disorders affect many individuals, impacting physical, psychological, and emotional aspects of their lives. Neurodegenerative disorders are diseases of the nervous system that cause progressive degradation of nerve cells, leading to loss of function and abilities. Examples of these debilitating disorders include Alzheimer’s Disease, Parkinson’s Disease, amyotrophic lateral sclerosis (ALS), Huntington’s Disease, and frontotemporal dementia. Several causes have been identified for neurodegenerative disorders, including genetic mutations, environmental toxins, viral or bacterial infections, poorly understood inflammatory mechanisms, and decreased levels of key neurotransmitters. In addition, sources suggest that, in certain cases, there may be roles for lifestyle choices, such as smoking, alcohol use, inadequate nutrition, and lack of physical activity. These disorders are characterized by progressive loss of nerve cells, leading to debilitating physical and mental impairment with no specific treatments capable of restoring lost function to the affected neurons. Symptoms may vary depending on the type of neurodegenerative disorder, but typically include progressive difficulty with movements, memory decline, confusion, and personality changes. Diagnostic procedures used to detect neurodegenerative disorders may include physical and neurological examinations, laboratory tests such as imaging techniques, and genetic tests for individuals with a high risk of inheriting the disorder. Treatment options currently available for neurodegenerative disorders includes symptom management and medication. While medicine can help to control symptoms, the underlying causes of a disorder cannot be reversed. In addition, certain lifestyle modifications, such as maintaining an active lifestyle, managing stress, and ensuring adequate sleep, have been shown to benefit patients. Furthermore, supportive care, such has counseling and educational services, can help patients cope with the various changes present in these types of disorders. Given the fact that these conditions are often debilitating and often cause long-term disability, exploring new options for treatments and therapy is of utmost importance. Recent years have seen exciting advances in the scientific understanding of these disorders, with much work being done to improve diagnosis and therapeutic methods in order to continue to improve patient quality of life.
Title : Personalized and Precision Medicine (PPM), as a unique healthcare model through biodesign-driven biotech and biopharma, translational applications, and neurology-related biomarketing to secure human healthcare and biosafety
Sergey Victorovich Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : Narrative medicine: A communication therapy for the communication disorder of Functional Seizures (FS) [also known as Psychogenic Non-Epileptic Seizures (PNES)]
Robert B Slocum, University of Kentucky HealthCare, United States
Title : Neuro sensorium
Luiz Moutinho, University of Suffolk, United Kingdom
Title : GBF1 inhibition reduces amyloid-beta levels in viable human postmortem Alzheimer's disease cortical explant and cortical organoid models
Sean J Miller, Yale School of Medicine, United States
Title : Study of resilience in cases of incest, father-daughter, step-father and step-daughter in the pre-pubber and puberous period among adult women and mothers: How to overcome the traumatisms of an incestuous relationship?
Daniele Lapointe, Laval University, Canada
Title : Traumatic Spinal Cord Injuries (tSCI) - Are the radiologically based “advances” in the management of the injured spine evidence-based?
W S El Masri, Keele University, United Kingdom