The Decline Theory in neurology revolves around the idea that the brain gradually declines in cognitive function and degenerates as an individual ages. This is a prominent area of study within the field of neurology, as aging individuals are most commonly affected by a variety of neurological disorders. This propensity for decline has been recognized for centuries, and a variety of underlying causes have been postulated to explain the phenomenon. Aging is associated with a broad range of changes within the brain, from neuronal death to decreases in neurotransmitterproduction to structural changes within the brain. Impairment in cognitive functioning, including memory and language, form the primary basis of the decline theory. Abnormalities in the hippocampus, the region of the brain most closely associated with memory formation, are among the most prominent aspects of the decline theory. For instance, hippocampal atrophy, or the tissue breakdown associated with aging, is known to play a role in age-related memory deficits. In addition to physical changes, the decline theory in neurology also involves an increasing tendency towards forgetfulness and impairments in executive functioning as well as language processing. Age-associated changes in brain plasticity can limit the individual’s ability to acquire new information, which can further contribute to decline in cognitive abilities. Deficits in visual processing, which markedly affect an older individual’s ability to function in everyday life, can also contribute to the decline theory. Other neurologically-based deficits, like dementia, might lead to an even greater magnitude of decline, though many of these conditions do not necessarily fit into the decline theory. While the causes of the decline in cognitive function with age are still debated and unknown, experts agree that age-related cognitive decline is a phenomenon affecting millions of aging individuals. With adequate preventive measures like exercise and a healthy diet, individuals may be able to stave off the effects of the decline theory to some extent; but even with the best of preventive measures, the decline theory in neurology remains a reality for the aging population.
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Robert B Slocum, University of Kentucky HealthCare, United States
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Title : Neuro sensorium
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Title : Traumatic Spinal Cord Injuries (tSCI) - Are the radiologically based “advances” in the management of the injured spine evidence-based?
W S El Masri, Keele University, United Kingdom