Progressive Supranuclear Palsy

Progressive Supranuclear Palsy (PSP) is a rare neurological degenerative disorder, characterized by progressive problems with walking, balance, vision, speech, and swallowing. It is caused by deterioration of certain areas of the brain, such as the basal ganglia and the cerebral cortex. There is currently no cure for PSP, and treatment is aimed at mitigating symptoms and slowing the rate of progression. PSP is estimated to affect about five people in 100,000 annually, and older adults are particularly susceptible. Symptoms typically manifest between the ages of 40 to 60, although younger adults and children may occasionally be affected as well. Early signs of PSP can be subtle and are often mistaken for signs of aging. Common early symptoms include poor coordination, stiffness, impaired vision, difficulty standing or walking, and a general lack of balance. As the disease progresses, individuals may fall more frequently, with falls potentially resulting in broken bones or other injuries. Dementia is often present in individuals with PSP, and may result in memory loss and confusion. Speech may be affected as well, causing slurring or difficulty forming words. Constipation, blurred vision, drooling, and difficulty in swallowing are all common symptoms of PSP, and can lead to severe weight loss. Numerous laboratories are currently researching causes and treatments of the disorder, and many believe it is due to a combination of both genetic and environmental factors. While there is still no known cause or cure for PSP, ongoing treatments such as medication, physical and occupational therapy, and speech therapy can help alleviate symptoms and slow the progression of the disease. Support groups and organizations may be available to individuals living with PSP and their families to provide information and assistance.