Corticobasal Syndrome (CBS) is a rare neurological disorder characterized by progressive and ultimately disabling degeneration of multiple areas of the brain. It leads to a movement disorder and typically affects one side of the body more than the other, resulting in weak and clumsy movements of limbs, as well as rigidity and increased reflexes, progression of dementia, and aphasia. CBS is considered a relatively rare disorder, with an estimated incidence of 1-2 cases per million each year. The exact cause of CBS is unknown, although it is thought to be related to a genetic mutation in the MAPT gene, which is involved in the development and maintenance of white matter. Other potential risk factors include advancing age, head trauma, and autoimmune disorders. CBS is a progressive and ultimately fatal condition, with no approved treatment or cure. Most individuals with CBS will require physical, occupational, and speech therapy to help manage their symptoms, which can include difficulty with coordination, movement, and balance problems, as well as difficulty speaking, understanding, and remembering. Medication may be prescribed to reduce tremors, muscle spasms, and rigidity and to control pain and depression. Botox injections may be recommended to help reduce tremors and rigidity. Surgery may be appropriate in some cases to improve muscle contracture and relieve pressure on the compressed nerves. In addition, supportive treatments, such as nutritional and psychological support, and physical and occupational therapy can help optimize an individual's functional abilities. In summary, Corticobasal Syndrome (CBS) is a rare neurological disorder characterized by progressive degeneration of multiple areas of the brain that can lead to difficulty with coordination, movement, balance, speech, understanding, and memory. There is no cure for CBS, but medications, injections, surgery, rehabilitation, and supportive services can help manage symptoms and slow the progression of the disorder.
Title : Perception and individuality in patient cases identifying the ongoing evolution of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Ken Ware, NeuroPhysics Therapy Institute, Australia
Title : Narrative medicine: A communication therapy for the communication disorder of Functional Seizures (FS) [also known as Psychogenic Non-Epileptic Seizures (PNES)]
Robert B Slocum, University of Kentucky HealthCare, United States
Title : Personalized and Precision Medicine (PPM), as a unique healthcare model through biodesign-driven biotech and biopharma, translational applications, and neurology-related biomarketing to secure human healthcare and biosafety
Sergey Victorovich Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : Neuro sensorium
Luiz Moutinho, University of Suffolk, United Kingdom
Title : GBF1 inhibition reduces amyloid-beta levels in viable human postmortem Alzheimer's disease cortical explant and cortical organoid models
Sean J Miller, Yale School of Medicine, United States
Title : Traumatic Spinal Cord Injuries (tSCI) - Are the radiologically based “advances” in the management of the injured spine evidence-based?
W S El Masri, Keele University, United Kingdom