Cerebral Blood Flow and Metabolism

The movement of blood through a network of cerebral arteries and veins that supply the brain is known as cerebral circulation. In an adult human, cerebral blood flow is generally 750 millilitres per minute, or roughly 15% of cardiac output. Arteries supply the brain with oxygenated blood, glucose, and other nutrients. In functional magnetic resonance imaging and optical imaging, cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRo(2)) are significant drivers of contrast. The relationship between CBF and CMRo(2) during cerebral activation, on the other hand, is still debated. Experimental experiments have led to inconsistent outcomes, despite the fact that most previous models tend to suggest a nonlinear interaction.