Aging disorder, also known as progeria, is a rare genetic condition that causes accelerated aging in children. It is very rare, affecting less than 1 in 8 million newborns. The exact cause of this disorder is unknown, however research has suggested that it may be due to a mutation in the LMNA gene. This gene produces a protein called lamin A, which is necessary for the structure and integrity of the nucleus of cells. People with progeria have a mutation in this gene which leads to an abnormal form of lamin A, leading to premature aging. The signs and symptoms of aging disorder tend to manifest in the first two years of life. Children with progeria often look older than they are, with their bodies appearing to age faster than normal. Symptoms can include thin hair and wrinkled skin, a prominent forehead, and a small lower jaw. Cardiovascular problems can also occur such as hardening of the arteries, joint stiffness, and a decrease in body fat. These symptoms can further lead to premature death due to heart disease. Currently, there is no cure for aging disorder. Treatment for progeria usually consists of addressing the various symptoms, such as using drugs to help reduce the symptoms of cardiovascular disease and physical therapy to help with joint stiffness. Due to the rarity of this disorder, research and treatment options are limited. However, great progress is being made as the result of the Progeria Research Foundation, which is working to further study this disorder and develop a cure. In conclusion, aging disorder is a rare genetic condition that affects a tiny portion of the population. It is characterized by premature aging symptoms, such as general appearance of an elderly person, cardiovascular problems and joint stiffness. Although there currently is no cure for this condition, research and treatment options are being developed to try and find one.
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