The full Neurology 2023 scientific program across 2 days — keynotes, oral presentations, and posters. Talks are ordered by program prominence within each day.
Day 1
- Oral
The association between pupil reactivity and cognitive measures among community-dwelling middle-aged and older adults
Yanjun Chen · University of Wisconsin Madison, United States
Aims : The pupillary light reflex (PLR) has been widely used to reflect visual function and brain activities, making it a potential biomarker for central nervous system (CNS) neurodegeneration. In this cross-sectional…
- Oral
Transcranial photobiomodulation on acute & subacute stroke patients
Juan Moreira · CNC / Gnosis Neurointegrative Center, United States
The limited time for a therapeutic window of intravenous thrombolysis have been a problem since it’s approval twenty eight years ago. The availability of a stroke team for thrombectomy or intravenous thrombolysis, and…
- Oral
Impact of exercise intensity on cerebral BDNF levels: Role of FNDC5/Irisin
Clemence Leger · University of Burgundy, France
Physical exercise (EX) is an essential approach to improve physical and brain health. It is well known that positive effects of EX on brain involve the upregulation of cerebral BDNF (brain-derived neurotrophic factor)…
- Oral
Case series on brain stimulation using TPS: Sustained therapeutic effects even in early Alzheimer’s disease
Ali Riza Gunes · Alexius/Josef Hospital Neuss, Germany
Background Alzheimer's dementia (AD) is the most common form of dementia worldwide, affecting 1.8 million people in Germany alone. Various forms of therapy are available, yet AD cannot be stopped, even with innovative…
- Oral
A randomized double-blind clinical trial on the efficacy of transcranial direct current stimulation in reducing alcohol consumption in non-abstinent patients with alcohol use disorder
Anastasia Demina · Dijon Bourgogne University Hospital, France
Background: Recent studies suggest that transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex (DLPFC) result in significant alcohol craving reduction. To study the impact of tDCS on…
- Oral
DNA process in fractal cells
Kais Bouallegue · University of Sousse, Tunisia
Computational biology faces the challenge of modeling the complex dynamical processes that underlie cellular functions, which evolve and change depending on internal functional requirements and external environmental…
- Oral
Comparison of the effects of sliding mechanism and reciprocating hinge-type medial linkage of knee-ankle-foot orthoses on walking ability in subjects with spinal cord injury
Mokhtar Arazpour · University of Social Welfare and Rehabilitation Sciences, Iran (Islamic Republic of)
Objectives: This study evaluated the efficacy of two different medial linkage mechanisms (sliding mechanism (SM) and medial linkage mechanism associated with reciprocating gait motion (MLRGM)) used on patients with…
- Oral
A novel deletion variant in CLN3 with highly variable expressivity is responsible for juvenile neuronal ceroid lipofuscinoses
Naser Gilani · Farabi Medical Laboratory, Iran (Islamic Republic of)
With more than 7,000 identified rare diseases and approximately 80 % being linked to genetic causes, diagnosing rare disease patients can often be difficult – resulting in lengthy, expensive, and emotional diagnostic…
- Poster
Transcranial laser photobiomodulation on posterior reversible encephalopathy syndrome
Juan Moreira · CNC / Gnosis Neurointegrative Center, United States
Posterior Reversible Encephalopathy Syndrome (PRES) have been described as a clinicoradiological syndrome characterized by acute ruptured of the Blood Brain Barrier and development of vasogenic edema secondary to acute…
- Poster
Neuro nanomedicine: Penetrating the blood brain barrier, delivering stem cells, treating stroke and meningitis, and so much more
Thomas J Webster · Interstellar Therapeutics, United States
Nanotechnology has revolutionized numerous industries, particularly medicine. Nanoparticles, nanotubes, drug delivery nanoparticles, and nanotextured neural probes are just several of many examples where nanomedicine is…
- Poster
The neurological basis of narcolepsy and how It affects daily life
Selin Edil · Hisar School, Turkey
Extreme daytime drowsiness, cataplexy, and an early beginning of rapid eye movement sleep are all symptoms of the chronic neurologic illness narcolepsy. It can be distinguished from other conditions that can induce…
- Poster
ADHD in children - Physical and psychological effects
Zeynep Elif Olmez · Hisar School, Turkey
Attention deficit/hyperactivity disorder which is popularly known as ADHD, is one of the most common mental illnesses affecting children. The effects of ADHD are known to affect a person in many areas of their life…
- Poster
Pain control theories
Begum Bulgurluoglu · Hisar School, Turkey
Neuroscientists Ronald Melzack and Patrick Wall put forth a revolutionary new theory of pain in the 1960s. Researchers at the time were having trouble explaining the phenomenon. While some asserted that the pain signals…
- Poster
The basis of decision-making
Mia Bahar · Hisar School, Turkey
Our days are assembled from thousands of small decisions: what to do, which way to go, how to respond, whether to partake, and our brain is made of many competing networks each with its own goals and desires. One neuron…
- Poster
Human brain mapping - The golden future of neuroscience
Lara Hanci · Hisar School, Turkey
The brain, being the most complex organ in the human body, can’t be completely understood with today’s technology. Therefore, there mostly aren't certain cures for brain diseases such as Alzheimer's disease, dementias…
- Poster
The application of brain-machine interface for prosthetic limb development
Lara Ann Tureli · Hisar School, Turkey
The applications of Brain-Machine Interface (BMI) are relatively recent. It is believed that BMI first started being researched and tested in the 1970’s. In its first applications, noninvasive methods were used to…
- Poster
Optogenetics on nonhuman primates
Arda Ozkurt · Hisar School, Turkey
Optogenetics is a method to activate or deactivate genetically modified neurons by using light. It has been a useful tool to discover new neural circuits since it was first used in 2004. In the early experiments…
- Poster
How trauma changes the brain
Nil Atay · Enka Schools, Turkey
Researchers are learning more about how traumatic events affect our brains physically. Changes in a brain mechanism used for learning and survival have been discovered by neurologists to play a role in how someone…
Day 2
- Keynote · Virtual
Intrathecal pain treatment & ziconotide
Georgios Matis · University of Cologne, Germany
Ziconotide is a synthetic, water-soluble cone snail venom-derived peptide with a molecular weight of 2,639 Daltons. It is a nonopioid analgesic that selectively binds to N-type voltage-sensitive calcium channels on…
- Keynote · Virtual
Identified new regulation of vesicular neurotransmitter transporters
Narinobu Juge · Okayama University, Japan
Neurotransmitter is an essential for synaptic transmission in the mammalian central nervous system, and is involved in all brain functions and in various neurological diagnoses. Vesicular neurotransmitter transporters…
- Keynote · Virtual
Relationships between sarcopenia, depressive symptoms, and mild cognitive impairment in Chinese community-dwelling older adults
Xiaoyu Chen · Shanghai University of Medicine and Health Sciences, China
Background: Mild cognitive impairment (MCI) represents an intermediate state between normal cognitive aging and dementia. We aimed to investigate the asso- ciation and mediation pathways of sarcopenia, including its…
- Keynote · Virtual
A new AAV tool specifically targeting Hippocampal CA2
Peng Siqi · Southeast University, China
Mice hippocampus contains three prominent subregions, CA1, CA3 and DG and is well regarded as an essential multiple task processor for learning, memory and cognition based on tremendous studies on these three…
- Keynote · Virtual
Sleep medicine: Modern medical research and acupuncture therapy
Lihong Li · The Second Affiliated Hospital of Zhejiang Chinese Medical University, China
Objective: Chronic insomnia disorder (CID) affects people's daytime function and is also a risk factor for many diseases. Targeted drugs have obvious side effects. The therapeutic effect of acupuncture on CID has been…
- Keynote · Virtual
Controlled reconstruction of cerebral networks: The possibilities of interactive brain therapy (stimulation) on the example of stroke (fMRI-EEG-neurofeedback research)
Nadezhda Khrushcheva · FIC FTM - Federal Research Center, Russian Federation
Neuroplasticity is the main characteristic of the adaptive properties of the brain, which ensure the self-organization of complex hierarchical and multi-relational connections within and between neural networks, during…
- Keynote · Virtual
Antibody-proteases as translational tools of the next-step generation to be applied for clinical applications in personalized and precision neurology practice
Sergey Victorovich Suchkov · N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Biomarkers enable pre-early diagnosis, guide targeted therapy and monitor the active ty and therapeutic responses across the diseases. Among the best-validated predictive biomarkers are autoimmunity-related ones to…
- Keynote · Virtual
Long-term memory acquisition and loss are dependent on PARP1- Erk2 synergism
Malka Cohen Armon · Tel-Aviv University, the Sackler School of Medicine and Sagol School of Neuroscience, Israel
We found a small piece in the puzzle of long-term memory. This finding identified the odd phenomenon implicating PARP1, a protein that initiates the repair of DNA breaks, in synaptic potentiation and in long-term memory…
- Keynote · Virtual
The neuroscience of mental disorders and the nature of consciousness
Rocco Gennaro · University of Southern Indiana, United States
In this talk I first review and discuss empirical evidence regarding brain damage and neural abnormalities associated with some psychopathologies and cognitive deficits, such as hemispatial neglect, agnosia…
- Keynote · Virtual
Treating chronic-stage stroke with hyperbaric oxygen therapy
Amir Hadanny · Aviv Clinics, United States
Due to damage brought on by cerebrovascular occlusion or hemorrhage, the brain struggles to obtain the same amount of oxygen to the afflicted regions of a stroke. A novel protocol utilizing hyperbaric oxygen therapy…
- Keynote · Virtual
Arteriovenous malformations: An update on models and therapeutic targets
Brandon Lucke Wold · University of Florida, United States
Arteriovenous Malformations (AVMs) are an anomaly of the vascular system where feeding arteries are directly connected to the venous drainage network. While AVMs can arise anywhere in the body and have been described in…
- Keynote · Virtual
Predicting noncoding disease causal mutations in central nervous system through deep learning
Wei Song · National Institutes of Health, United States
The majority of GWAS mutations are in noncoding regions, making it challenging to pinpoint the true disease-causal mutations in a complex linkage disequilibrium (LD) block and quantify their causality. To address this…
- Keynote · Virtual
The role of newborn screening in the era of gene therapy for neuromuscular disorders
Geetanjali Rathore · University of Nebraska Medical Center, United States
Neuromuscular disorders (NMD) are debilitating conditions that often lead to early morbidity and mortality due to progressive weakness. In the last decade, the treatment of NMD has undergone a remarkable advancement and…
- Keynote · Virtual
Recent advances in brain imaging
Mohit Saxena · Northwestern University Feinberg School of Medicine, United States
The talk will elucidate how certain imaging techniques that are currently used in research can be applied to clinical diagnoses and help the surgeons, neurologists and epileptologists make better decisions. Recent…
- Keynote · Virtual
Neurogenesis Hypothesis with a Case Study-Phase 2A Clinical Trials of NA-831 for the Treatment of Alzheimer's Disease
Lloyd L Tran · Biomed Industries, Inc., United States
In the hippocampus, new neurons are generated throughout life via a process called adult hippocampal neurogenesis (AHN). In mild cognitive impairment (MCI) and mild to moderate AD (early AD), AHN is reduced suggesting…
- Keynote · Virtual
Evidence of the protective effect of allopregnanolone analogues in alzheimer’s disease experimental models
Nwife Okechukwu · University of Strasbourg, France
Alzheimer's Disease (AD) is a major cause of cognitive/memory impairment and dementia. Amyloid beta (Aβ) is an extracellular 39-43 residue long peptide whose aggregation is associated with Alzheimer’s disease (AD) and…
- Keynote · Virtual
Examining bilateral cortical activity in patients with parkinson`s disease and healthy controls during speech production: A fNRIS study
Anne Dorothee Rosch · University of Edinburgh, United Kingdom
Background: According to the “Hemispheric Asymmetry Reduction in older Adults” model (HAROLD; Cabeza, 2002) healthy elderly (HE) may show bilateral cortical activity patterns compared to younger subjects showing more…
- Keynote · Virtual
Brain-Machine teaming: Recent advances for neural language decoding from EEG Signals
Ji Hoon Jeong · Chungbuk National University, Korea, Republic of
Brain-machine teaming is a collaborative interfacing system between the human brain and external machines. It is a bidirectional communication concept based on the brain-machine interface (BMI). Especially…
- Keynote · Virtual
Vestibular Migraine
Elena Illarionova · Smolensk State Medical University, Russian Federation
The current state of the problem of polymorphism of the clinical picture of vestibular migraine and objectification of the vestibular component remains unresolved and require further research.The purpose of our study…
- Keynote · Virtual
Looking for new antidepressants - interactions between COX-2 and glutamatergic receptors
Katarzyna Stachowicz · Polish Academy of Sciences, Poland
Depression is one of the main mental disorders requiring hospitalization, fraught with the incidence of suicide attempts. Statistics indicate that depression is twice as common in women as in men; it affects middle-aged…
- Keynote · Virtual
Evaluation of anterior versus posterior circulation acute ischemic stroke with clinico-topographic correlations and relationship with early mortality-based scale predictions
Esra Demir Unal · Nevsehir State Hospital, Turkey
Background: Posterior circulation ischaemic strokes (PCIs) are a clinical syndrome associated with ischemia or embolic occlusion of posterior circulation and differ from anterior circulation ischaemic strokes (ACIs) in…
- Keynote · Virtual
Manual therapy and segmental stabilization in the treatment of chronic pain
Joao Rafael Rocha Da Silva · Connect Life Rehabilitation and Performance, Brazil
Pain is one of the most frequent complaints of patients, being responsible for causing damage to the public health system, disability, and loss of functionality to patients. Understanding the different levels and types…
- Keynote · Virtual
rhFGF18 and rhGDF11 for the treatment of ischemic stroke
Alex Goraltchouk · Remedium Bio, Inc., United States
Objective: The goal of our research was to objectively evaluate the safety and efficacy potential of two investigational treatment regimens using rhFGF18 and rhGDF11 for the treatment of ischemic stroke. Background…
- Keynote · Virtual
Brain-Machine teaming: Recent advances for neural language decoding from EEG Signals
Keun Tae Kim · Chungbuk National University, Korea, Republic of
Brain-machine teaming is a collaborative interfacing system between the human brain and external machines. It is a bidirectional communication concept based on the brain-machine interface (BMI). Especially…
- Keynote · In-Person
Remote ischemic conditioning as an adjunct intervention in ICU traumatic brain injury patients: Preliminary findings on injury biomarkers from a randomized controlled trial
Zahra Khan · University of Toronto, Canada
Introduction: Management of Traumatic Brain Injury (TBI) is currently aimed at secondary brain injury prevention that results from brain ischemia. Remote ischemic conditioning (RIC) is a non-invasive intervention that…
- Keynote · In-Person
Pediatric febril status epilpeticus. Case serie of children admitted at Hospital de Niños Dr. O. Alassia Santa Fe, Argentina, period 2015 until 2018
Betiana Comas · Hospital de la Baxada Teresa Ratto, Argentina
Introduction: The status epilepticus is a neurological emergency that needs intensive measures and also has high mortality. The International Leage Against Epilepsy (ILAE) in 2015 sets a new definition: is a condition…
- Keynote · In-Person
Biosensor with acetyl-choline-esterase enzymatic receptor and si-nanoporous layer as entrapping element - Extrapolated to para-sympathomimetic pesticides
Cristian Ravariu · Polytechnic University of Bucharest, Romania
The Acetyl-cholinesterase enzyme, also noted AcHE, has the code - EC 3.1.1.7, being an enzyme that degrades by hydrolysis the acetylcholine (AcH) neurotransmitter in choline and acetate. In vivo, this enzyme is found at…
- Keynote · In-Person
C-terminal domains of GluA2 regulate amyloid-beta induced synaptic and cognitive impairments
Qiaoyun Ren · Southeast University, China
Objective: Synaptic dysfunction is one of the early symptoms of AD, which occurs much earlier than the formation of amyloid plaques and neurofibrillary tangles. Synaptic function is closely related to the number and…
- Keynote · In-Person
Neuroscience of addiction
Dalya Sezercan · Hisar School, Turkey
Addiction can be defined as an irresistible desire for an object, individual or entity although it is known to be harmful to the person physically or psychologically. In addiction physical dependence is explained as…
- Keynote · In-Person
The effect of pelvic floor muscle training alone or in combination with multi-session anodal transcranial direct current stimulation in the treatment of sexual dysfunction in female patients with multiple sclerosis
Mona Ramezani · Semnan University of Medical Sciences, Iran (Islamic Republic of)
Introduction: Sexual Dysfunction (SD) following dysfunction of the pelvic floor muscles (PFM) is perceived to be more common in women with Multiple Sclerosis (MS) than in the general population. Studies report a…
- Keynote · In-Person
Mindfulness-Based Protocol for Recovery from Stroke (MBRfS): A pilot study
Lori Gray · Western Michigan University, United States
Decades of research suggest that Mindfulness-Based Stress Reduction (MBSR) training supports a greater capacity to live with chronic medical conditions and contributes to lowering stress levels. This paper introduces a…
- Keynote · In-Person
The mechanism of NLG1 regulating ASD-like (restricted and repetitive) behaviors
Dandan Lv · Southeast University, China
Objective: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with two core symptoms, namely repetitive stereotyped behaviors and impairments in social interaction. Neuroligin1 (NLG1) is one of…
- Keynote · Virtual
Enhancing epilepsy diagnosis using automated temporal windowing for frequencies and entropies feature extraction computing
Ridha Djemal · ENIS Sfax University, Tunisia
The diagnosis of epilepsy relies on careful analysis of electroencephalograph (EEG) records to understand the underlying mechanisms of epileptic disorders. Due to noise interference, filtering is necessary before…
- Keynote · Virtual
What’s Leqembi got to do with alzheimer dementia
Zung V Tran · Biomed Industries, Inc., United States
Lecanemab is the humanized IgG1 version of the mouse monoclonal antibody mAb158, which selectively binds to large, soluble Aβ protofibrils [1]. On January 6, 2023, Lecanemab (Leqembi) was approved by the FDA under an…
- Oral · Virtual
Neuro Physics Therapy (NPT) shows to be a highly effective psychophysical treatment for its patients enduring advanced Facio Scapulohumeral Muscular Dystrophy (FSH, FSHD) symptoms, with significant sustainable generation of lost or highly compromised functions being realized in very small time scales
Ken Ware · Neurotricional Sciences Institute, Australia
Facioscapulohumeral muscular dystrophy (FSHD) is one of the most frequent hereditary muscle disorders. It is said to be a ‘genetic’ muscle disorder in which the muscles of the face, shoulder blades, and upper arms are…
- Oral · Virtual
Neuroimaging by evaluation nerve repair and remodeling of acupuncture in children with cerebral palsy
Zhenhuan Liu · Nanhai Maternity and Children Hospital Affiliated to Guangzhou University of Chinese Medicine, China
Objective: To investigate the effect of and Acupuncture on brain plasticity and motor development in children with cerebral palsy. Investigate effect on mechanism of apoptosis of brain nerve cells, regulating the…
- Oral · Virtual
Addiction: A problem of motivation, free will, or self-destructive behavior?
Roy F Baumeister · University of Queensland, United States
Popular stereotypes of addiction emphasize loss of free will, sometimes based on irresistible urges. The recently popular “brain disease” theory of addiction likewise emphasizes on the inability to stop using despite…
- Oral · Virtual
Live test for chronic wasting disease based on consistent association with an extreme thermoacidphilic bacterium
Frank Owen Bastian · Bastian Enterprises, United States
The problem with controlling chronic wasting disease (CWD) infection in ruminants is there is no reliable live test for this devastating fatal encephalopathy. Our strategy is to use a disease biomarker to develop a live…
- Oral · Virtual
Using expressive arts exercises to promote self-care among neurologists and caregivers: An experiential overview
Juliana Melody Fort · Louisiana State University Health Shreveport, United States
Research suggests that the cumulative stress of caring for a person with a chronic neurological disorder can contribute to burnout, both among physicians (“physician burnout” and patient families (“caregiver burnout…
- Oral · Virtual
Personalized and Precision Medicine (PPM) as a unique healthcare model to be set up through biodesign, unique translational applications and upgraded business marketing to secure the human healthcare, wellness and biosafety
Sergey Victorovich Suchkov · N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Policy formation in the field of individual health promotion and protection is one of the priority tasks of national healthcare systems. Canonical health care is becoming increasingly unaffordable in most of the…
- Oral · Virtual
Neural stem cell-derived exosomal mir-9a-5p overexpression improving neurogenesis in ischemic stroke
Lukui Chen · Southern Medical University, China
Background: Ischemic stroke is a serious disease which can result in physical disability and death. The protective effect of miRNA up-regulated exosomes derived from neural stem cells (NSCs) on ischemic stroke and its…
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