Title : The neurological challenges of schizophrenia : A study on Extrapyramidal symptoms in schizophrenia
Abstract:
In India, a considerable portion of the population is affected by mental illnesses due to inadequate coverage of mental health care. Psychiatric disorders pose increasing challenges from both sociological and economic standpoints. Physicians confront difficulties in optimizing antipsychotic medication dosages to balance effectiveness and minimize side effects. Extrapyramidal symptoms (EPS) are movement disorders, arising from dopamine-receptor-blocking medications, complicate patient management with symptoms like acute dystonia, akathisia, parkinsonism, and tardive dyskinesia. This research focuses on the demographic and clinical profiles of patients undergoing antipsychotic treatment for schizophrenia, with a specific emphasis on movement disorders caused by antipsychotic medications. A machine learning model predicting EPS factors, based on patient data, has been developed to estimate the probability of symptom occurrence. Utilizing statistical tools such as Wilcoxon rank-sum and Chi-square tests, baseline disparities between EPS and Non-EPS groups were assessed. Factor analysis revealed key factors to EPS, and a partial correlation network showed positive correlations between BMI, Chlorpromazine equivalent daily dose, and duration of Schizophrenia. With a notable 38.3% EPS prevalence, Parkinsonism emerged as a significant subtype. The collaborative efforts of Indian Institutes of Technology and the All-India Institute of Medical Sciences, Jodhpur underscores the research's significance in refining therapeutic approaches for schizophrenia. Insights from this study hold promise for enhancing personalized care in India's mental health landscape. This abstract aims to offer insights into the challenges associated with antipsychotic treatment and presenting innovative approaches to address the challenges faced by patients in the treatment of schizophrenia and its associated adverse effects.
Audience Take Away Notes:
- This presentation provides attendees with a profound understanding of the challenges inherent in antipsychotic treatment within the realm of Indian mental health, placing a specific emphasis on the prevalence and impact of Extrapyramidal Symptoms (EPS) on patient management.
- Attendees will gain valuable insights into the intricate link between psychiatry and neurology, illuminating the complex interplay of factors influencing the manifestation of EPS.
- The discussion extends beyond patient challenges to address the difficulties faced by physicians, healthcare providers, and caregivers in managing these symptoms effectively.
- The audience will benefit from innovative approaches outlined in the presentation, offering fresh insights and practical strategies for symptom management.
- This presentation serves as a pivotal resource for faculty, providing them with novel perspectives and tools to
- enhance their understanding and approach to the nuanced management of antipsychotic-induced symptoms in the context of mental health.
