Title : Neuroinflamation and venous lesion of the neck veins role in inner ear disease
Abstract:
Purpose: To evaluate the relationship between Meniere’s disease and chronic cerebrospinal venous insufficiency (CCSVI) using ultrasonography, magnetic resonance imaging, and venography and the effectiveness of angioplasty for reducing the symptoms of inner ear disease.
Materials and Methods: A total of 1112 patients diagnosed with definite MD who had not experienced improvement with medical and surgical therapy underwent duplex ultrasonography and MRI to diagnose the presence of venous stenosis of the neck.
Results: A total of 867 (80%) MD patients were diagnosed with venous lesion of the neck. In the healthy population, was evident in only 12% of patients. Venography was performed in 434 patients to confirm the diagnosis of CCSVI. In 80% of these patients, PTA of the IJVs and/or azygos veins was effective for treating the signs and symptoms of CCSVI and MD.
Conclusions: Venous lesion of the neck was prevalent in patients with MD. Most patients responded favorably to PTA. Our results suggest a possible etiological relationship between venous stenoses and MD that warrants further investigation.
Keywords: CCSVI–chronic cerebrospinal venous insufficiency; PTA–percutaneous transluminal angioplasty; IJV– internal jugular vein.
