Title : EEG application pre-and post-cerebral cortex disconnection surgery in intractable epilepsy
Abstract:
Cerebral cortex disconnection surgery is a surgical treatment method for drug-resistant epilepsy patients. By this surgical technique,the connection between the epileptic cerebral tissue and its related structures and adjacent brain tissue were disconnected completely. It means the disconnected brain tissure (including one cerebral region, one lobe or one hemisphere) can be exit almost intact but can not perform its original function or cause seizures, So seizure free can be attained after surgery. According to the location of the disconnection, the corresponding disconnection surgeries can be divided into frontal lobe disconnection, parietal lobe disconnection, occipital disconnection, insular and periinsular cortex disconnection, temporo-parieto-occipital disconnection, Hemispherotomy (also called functional Hemispherectomy), and so on. Cerebral cortex disconnection surgery can achieve the effect of surgical resection, but there are fewer surgical complications, so it’s performed widely in epilepsy surgery. Video EEG is one of the important tools for epilepsy during its diagnosis and treatment. For refractory epilepsy video EEG is more important during preoperative evaluation for epilepsy surgery. It can provide not only the localization information about the epileptogenic zone, but also an important content of postoperative follow-up, providing a basis for surgical prognosis judgment, efficacy evaluation, and adjustment or from reduction to withdrawl of anti-seizure drugs. This lecture will provide an overview of the development of cerebral cortex dissection in China over the past 20 years. We also review the characteristics of electroencephalography (EEG) before and after cerebral cortex dissection surgery and its relationship with its outcomes. And also I will share our experience based on our case studies. Finally, some hypotheses and ideas are proposed for the future application of VEEG for cerebral cortical dissection surgery.
Audience Take Away Notes:
- Video EEG has been a popular and useful method in epilepsy, especially in presurgical evaluation. Cerebral cortex disconnection surgery is one epilepsy surgery procedure. Our presentation will discuss:
- The development of the cerebral cortex dissection surgery in China in the past 20 years, especially the hemispherectomy;
- What’s the characteristics of the VEEG in the patients with refractory epilepsy before cerebral cortex dissection surgery?
- What’s the characteristics of the VEEG in the patients with refractory epilepsy after cerebral cortex dissection surgery?
- What’s the possible value of the VEEG in the evaluation for the prognosis of cerebral cortex dissection surgery?
- What we can do in the future by VEEG in the patients after cerebral cortex dissection surgery?
- I think what I presentation will be useful and helpful in your future work.
