Title : A Novel, Safe, Effective Treatment for Opioid Use Disorder
Abstract:
Schiffer has proposed and tested and published his novel hypothesis about the relation between the cerebral hemispheres and psychopathology. His ideas come out of his clinical observations and the split-brain studies and are combined in what he has termed dual-brain psychology (DBP), which posits that one brain hemisphere, left or right, as a trait in an individual is more affected by early complex traumas and he has found in his clinical practice and in two published randomized control trials that activating the healthier hemisphere with unilateral transcranial photobiomodulation (UtPBM), near-infrared mode has been highly successful in treating a range of psychiatric disorders including opioid use disorder. Here we will focus on the latest NIH-funded trial in which we sought to treat 39 participants mostly from CraigsList.com who reported significant opioid cravings. 19 participants were treated with an active LED and 20 with a sham, which used the identical device with foil over the LED. The study was conducted and 2 sites, both of which reported similar results. The participants were treated twice a week for 4 weeks with 3 weekly follow-ups. The results showed that from baseline to the 3rd follow up there was a highly significant better improvement in the active group versus the sham and at the end of treatment and at the 3rd follow-up with an effect size was 1.5. At the McLean site there was also a very significant decrease in opioid use in the active group but not sham. In Schiffer's private practice he combines this UtPBM treatment with psychotherapy based on DBP, but in this control study, participants received only a twice weekly UtPBM treatment or sham. We feel the study show that UtPBM can be used as a stand-alone treatment or in combination with buprenorphine. From private practice, we feel it is greatly augmented when combined with dual-brain psychotherapy and we feel that this randomized control trial supports the novel hypotheses of DBP from which the UtPBM evolved. There were no adverse reactions observed or reported.
What will audience learn from your presentation?
- The audience will learn the theory and application of Dual-Brain Psychology with and without the use of unilateral transcranial photobiomodulation
- This will help clinicians in psychology and researchers in neuropsychiatry learn a new paradigm that, while novel, is supported by 30 years of experimentation and 27 publications and a book. The new paradigm will advance research and clinical applications.
